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1 Although some studies have reported lower limb subcutaneous adipose tissue mass in Cushing patients, 46 when quantified by whole-body magnetic resonance imaging (MRI) (the gold standard for assessment of body composition), limb subcutaneous adipose tissue in Cushing patients was not different in comparison with controls

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The mechanism of this combined effect appears to be sequential: TB-500 mobilizes and migrates repair cells to the injury site (via actin regulation and chemotactic signaling), while BPC-157 creates the optimal local microenvironment (via angiogenesis, growth factor expression, and NO modulation) for those cells to perform effective repair once they arrive

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