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Summary: Cagrilintide and retatrutide are investigational injectable medicines being studied for obesity and type 2 diabetes in men, targeting multiple hormonal pathways to reduce appetite, improve blood glucose control, and increase energy expenditure, but neither is currently licensed in the UK

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In addition, it does not exclude the possibility that the conformational changes of the polymerase through rhythmic relaxation and contraction, also known as molecular respiration, facilitates the template RNA to be continuously squeezed into the catalytic pocket and also plays a role in the translocation of the template during RNA synthesis