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It is based on current scientific literature and research trends

109 In a placebo-controlled trial with 28 healthy subjects reporting no or mild sleep difficulties, taking a single dose of a protein supplement with 4.8 grams of tryptophan reduced sleepiness and increased sustained alertness the next morning compared with a low-tryptophan protein supplement

Limitations The study has a limited number of participants (90 patients), which may restrict the generalizability of the results to the broader population

GhorbaniZToghaMRafieePAhmadiZSRasekh MaghamRHaghighiSet al

[Google Scholar] Scholte HR, Rodrigues Pereira R, de Jonge PC, Luyt-Houwen IE, Hedwig M, Verduin M, Ross JD

Here are the genetic variants related to histamine intolerance (check for multiple variants in AOC1 plus HNMT)