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Demonstration of good to excellent reproducibility of GSH measures by all 13 studies in 13 ROIs distributed throughout the brain (limbic (N = 4), frontal (N = 4), temporal (N = 2), parietal (N = 1), occipital (N = 1), and the corona radiata (N = 1)) adds weight to age-specific GSH level findings

Increased glutathione in plants overexpressing -ECS is associated with enhanced resistance to heavy metals and certain herbicides (Zhu et al., 1999a

This entry excludes any dosing, injection frequency, or cycle-length information

Mild redness or soreness at the injection site is most common

But if conditions that support free radical formation in the cell persist, severe oxidative stress can occur, with some very unhealthy potential consequences

These data indicate that NO-associated redox reactions occurring in the mitochondria play an important role in ASD, although the exact mechanisms implicating NO in this role need further investigation