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doi: 10.1007/s11357-017-9970-1 [DOI] [PMC free article] [PubMed] [Google Scholar] 166.Yadav RK, Mehan S, Sahu R, et al

I., Giukova A

Discoloration around the mouth or eyes: These areas are especially sensitive to fluctuations in melanin production

Rodent studies show they are causally linked, suggesting the presence of biological pathways mediating this link

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