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[DOI] [PubMed] [Google Scholar] 56.Crefcoeur L

Recent evidence suggests that aberrant brain-gut pathways, mitochondrial enzymopathies, gastrointestinal motility disorders, calcium channel abnormalities, and hyperactivity of the hypothalamic-pituitary-adrenal axis in response to a triggering environmental stimulus are involved in the CVS development ( This review was developed by a joint task force of the Italian Society of Pediatric Gastroenterology Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP) to propose future research directions

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The work on animals in this study was carried out in accordance with the rules of the Institutional Review Board of the Ethical Committee of Animal Care and Use in Scientific Research of the Faculty of Veterinary Medicine, Minia University