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Immunoblot and quantification of indicated proteins in primary hepatocytes isolated from mice liver treated with BSA, 200 M palmitic acid (PA), oleic acid (OA), or linoleic acid (LA) for 4 h after overnight serum starvation, and immunoblot quantification of P-eIF4E/eIF4E in the AML12 cells and primary hepatocytes in response to BSA or different fatty acids (n = 3 biological independent samples)

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We investigated whether acetyl-L-carnitine (ALC), a metabolite linking energy and lipid metabolism, regulates oligodendrocyte (OL) myelination and rescues behavioral deficits in a post-weaning social isolation (PWSI) mouse model