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Prolongation of intestinal transit time was also speculated in our previous clinical study for the gradations observed in the early (absorption) phase of the plasma concentration-time profiles of kratom alkaloids

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BPC 157 was given per-orally in drinking water (10 g/kg, 12 ml/rat/day) until sacrifice, or 10 g/kg or 10 ng/kg was given intraperitoneally once daily, with the first application at 30 min after surgery and the last application at 24 h before sacrifice

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pH compatibility : The slightly acidic pH of bacteriostatic water is compatible with most peptide structures and prevents premature degradation

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As a proposed zonulin antagonist and tight-junction regulatory peptide, the use of LA may prove useful for other patient indications given current data in both small and large animal models of injury

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