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Similar to the human GCLC, up-regulation of the human GCLM by -NF involved binding of transcription factor Nrf2 (possibly in complexes with other Jun or Maf proteins as in GCLC) to a functional ARE/EpRE site located at 302 of the human GCLM [104,134]

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The Head-Up Tilt table test as a measure of autonomic functioning among patients with myalgic Encephalomyelitis/Chronic fatigue syndrome

Preprint at (2018)

In other words, if the average person has a 50% chance of developing insulin resistance then patients with thyroid disease probably have about a 70% chance of having the same condition

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