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Lindsay Allen said that smaller, repeated doses of B12 during breastfeeding, rather than a single one-a-day supplement, appear to be more effective for the mothers B12 status (NASEM, 2020)

[27] Additionally, anyone with Lebers hereditary optic neuropathy (a rare inherited eye disease) must avoid cyanocobalamin injections, since B can precipitate rapid worsening of that condition

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For the adults 60, the people who were homozygous for one of the polymorphisms (31% of the population studied) had average MMA levels of 420 nmol/l

www.cdc.gov

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