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Certain bacteria in the gut microbiota may directly detect chemicals such as glucose, amino acids, and fatty acids 28

Dong P, et al

W.ChungI

This review provides a comprehensive overview of recent advances in the rational design, chemical synthesis, and biological evaluation of promising XO inhibitors for the treatment of hyperuricemia and gout

This work was funded by ShanghaiTech University, the National Program on Key Basic Research Project of China (2018YFA0507004 to W.S.), National Natural Science Foundation of China (31971362, 32171439 to W.S.) and Shanghai Natural Science Foundation Grant (18ZR1425100 to X.H.)
