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Moreover, properly harnessing the Nrf2/HO-1 axis while managing its potential pro-ferroptotic risks may help maintain redox balance and curb iron overload, thereby offering an additional strategy to alleviate ferroptosis-driven damage in OA (202)

Reduced negative surface charge on arterial endothelium explains accelerated atherosclerosis in type 2 diabetic patients

Open questions include tissue-selective delivery, chronic dosing effects on one-carbon metabolism, and interactions with NAD precursor strategies [14,8,9]

NS seeds are a rich source of antioxidants, notably phenolic and flavonoid compounds, which contribute significantly to their potent DPPH radical scavenging activity (Mahmoud et al

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