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The role of amino acid transporters in GSH synthesis in the blood-brain barrier and central nervous system

Early diagnosis permits timely initiation of therapeutic measures, which can mitigate the evolution of nerve damage

10.1021/acsnano.8b09387 43 LiuJ.WuM.PanY.DuanY.DongZ.ChaoY.et al (2020)

PINK1 deficiency reduces activation of STAT3 and AKT, which negatively regulate inflammatory responses [14]

The key strength of this study is that our patient population and study design are representative of a real-world clinical setting, including patients with various baseline HbA 1C concentration, weight, and BMI values who are taking other concomitant antihyperglycemic medications and have a history of prior GLP-1 RA and/or insulin use