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Despite treatment, the woman is unable to verbalize or care for herself, requiring an ongoing feeding tube for nutritional support.
149 An alternative means of linking a bile acid to a platinum(II) center involves conjugation to the nonleaving group ligands, a strategy that has afforded complexes demonstrating activity in cultured cells via a mechanism of action similar to that of cisplatin
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This mismatch is further complicated by the fact that standard thyroid panels typically exclude fT3 and rT3 measurements, which can render tissue-level hypothyroidism undetectable through conventional testing
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