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One of the most important upregulated epigenetic modifiers during disease progression is EZH2, a histone methyltransferase whose mRNA and protein levels are strongly associated with prostate cancer progression [71]

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MRI scans and functional connectivity tests showed that choline likely influences working memory in menopause.[ref] A prior study showed that higher dietary choline and betaine intake was associated with slower cognitive decline in women as they age.[ref] Thus, for women experiencing brain fog in menopause, increasing dietary choline or supplementing with choline may be beneficial