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Description
CPT-1 deficient patients are treated with dietary management strategies such as frequent feedings with medium-chain triglycerides and strict avoidance of fasting [15]

The AC/FC ratios increased in the effective group and decreased in the noneffective group at any point after baseline, although not significantly

There are multiple proposed mechanisms for its use in ALS, including mitigating oxidative stress by up-regulating nuclear factor erythroid 2-related factor 2 (Nrf2), glutathione, and heme oxygenase 1 (HO-1) [175], promoting mitochondrial function by increasing serum levels of ATP [176], and protecting against glutamate excitotoxicity [177]

2021;2(6):e31726

[ Links ] Winther B, Jackson D, Mulroy C, MacKay M

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