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Its potential to help comes from two angles: its anti-inflammatory properties can reduce the chemical irritation of the nerve root, and its neuroprotective effects may help protect the nerve from compressive damage and support its healing

270 This phosphorylation enhances the binding of p62 to ubiquitinated substrates and LC3, thereby promoting autophagosome engulfment and subsequent lysosomal degradation of both p62 and damaged mitochondria

Overdose of APAP depletes glutathione reservoir, leading to the rise of NAPQI level

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Conclusion: Grx2s anti-apoptotic and cytoprotective roles may make it a potential drug target to treat oxidative stress-induced diseases Despite being overlooked, research throughout the years has portrayed Grx2 as a capable and robust antioxidant enzyme through direct detoxification of free radicals, cytoprotection, and anti-apoptotic abilities [5, 23]