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Also, the fact that two benign tumors - oncocytoma and non-invasive papillary urothelial pTaG2 low grade carcinoma - showed occasional E-Cadherin loss suggests that reduced or absent E-Cadherin immunostaining is not invariably linked to tumor malignancy

Knapen LM, van Dalem J, Keulemans YC, van Erp NP, Bazelier MT, De Bruin ML,

You'll notice it as reduced capacity and a loss of punch

An accurate diagnosis is crucial to design a reasonable medical strategy, including management options, malignant transformation surveillance, and psychological support

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MPNST is a highly aggressive tumor with a high rate of local recurrence and pulmonary and visceral metastatic spread