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In the reviews by Ng et al

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Compared with the HO-1 +/+ mice (21.4 1.8%), the myocardial infarct area significantly reached at 36.4 20% in HO-1 deficient mice

The topical application delivers concentrated peptide directly to scarred areas where it's needed most

However, neither of these drugs has improved OA symptoms in human clinical trials to date, likely because of the dynamic joint environment

[DOI] [PubMed] [Google Scholar] 211.Ronnebaum SM, Ilkayeva O, Burgess SC, Joseph JW, Lu D, Stevens RD, et al
