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Significant gaps remain, particularly the lack of treatments with adequate safety and true disease-modifying potential capable of addressing key pathological drivers such as neuroinflammation, mitochondrial dysfunction, impaired proteostasis and toxic protein aggregation ( Polygonum cuspidatum ), curcumin ( Curcuma longa ), epigallocatechin gallate (EGCG
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Research has investigated its role as a major antioxidant, electrophile scavenger and substrate for glutathione peroxidase and glutathione S-transferase enzymes in oxidative stress and detoxification pathways
11 Therefore, identifying an effective biomarker among MTHFR 677 TT genotype to guide folic acid treatment is important for reducing first stroke risk
The Intersection between Bacterial Metabolism and Innate Immunity
