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97 Binding of a benzodiazepine molecule to its neuronal benzodiazepine receptor increases the effect of GABA on its GABA A -receptor

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The pathway is divided into two main phases: an irreversible oxidative phase and a reversible non-oxidative phase

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Co-crystal structures of GSTO1 bound to inhibitors showed a covalent association with the active site cysteine (C32) with additional hydrophilic and hydrophobic interactions in the H-site