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Their antioxidant mechanisms are linked to their influence on the pathways and enzymes within mitochondria

3b) and was correlated with reduced InsP 7 in tissues (Fig

Avan and colleagues demonstrated that both these drugs are neurotoxic because they induce DNA adduct accumulation and the inhibition of DNA repair pathways, such as the extracellular signal-regulated kinase 1/2, c-Jun N-terminal kinase/stress-activated protein kinase, and p38 mitogen-activated protein kinase pathways, which ultimately results in apoptosis [78]

Unfortunately, hardly any genetic markers have so far been identified as predictors of efficacy or ADRs that could be useful for the development of dosing guidelines [30]

Its native range spans multiple Chinese regions (northwest, southeast, north, east, and central) (Xu et al., 2025), with a global distribution extending across East Asia (Japan, Korea) and Southeast Asia (Vietnam, Thailand, Myanmar) and introduced populations in Europe and North America (Bown, 2014

detoxifies amines (serotonin, melatonin, histamine, tyramine, and all of the catecholamines: dopamine, norepinephrine, epinephrine), phenols (salicylic acidaspirin, cannabinoids, estradiol, and BPA), and many other chemicals