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More than 210 recent works of literature are covered in this review

Considering that nearly all diabetic patients take metformin and many also proton pump inhibitors (mostly for gastric protection because of concomitant use of aspirin or other antiplatelets for cardiovascular complications of diabetes), it is not surprising that B 12 deficiency is common in diabetic patients

This multiplex strategy may be particularly valuable for solid tumors that have historically been resistant to immunotherapy

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