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Metformin and other natural products known to activate AMPK are currently being tested in clinical trials to determine their efficacy in treating various cancers (reviewed in [121])
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Its worth noting, however, that this population was likely carnitine-depleted, so results may not reflect what younger, healthy adults would experience
J Biol Chem 271:2507125078 [DOI] [PubMed] [Google Scholar] Runnels LW, Jenco J, Morris A, Scarlata S
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Chen EJ, Sowalsky AG, Gao S, Cai C, Voznesensky O, Schaefer R, et al
