herxing from glutathione Redox-responsive nanomedicine beyond glutathione: harnessing reactive oxygen species and emerging endogenous triggers for precision drug delivery Fear of a Herxheimer Reaction

The supply of GSH precursors from astrocytes to neurons does not only increase the GSH content in neurons but also improves the resistance of neurons to various adverse treatments, including induction of oxidative stress and application of toxins (Table 2), demonstrating the importance of the astrocytic cysteine supply for neuronal GSH synthesis

Design and synthesis of systemically active metabotropic glutamate subtype-2 and -3 (mGlu 2/3 ) receptor positive allosteric modulators (PAMs): pharmacological characterization and assessment in a rat model of cocaine dependence

Badania nad gojeniem ran sugeruj, e codzienne stosowanie przez 2-4 tygodnie przyspiesza proces regeneracji i zmniejsza ryzyko powstawania blizn

528 Excess irons can promote the progression of atherosclerosis by affecting macrophages, and a balanced intracellular iron environment is crucial in alleviating atherosclerosis

Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity

Read about all our current research projects The MS Society Cambridge Centre for Myelin Repair is dedicated to understanding more about the myelin repair process, particularly focusing on the OPC response