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Many patients benefit from bi-weekly or monthly treatments

High-dose oral B12 supplements are available over the counter for a few dollars per month, while injection visits typically involve copays, administration fees, and the time cost of repeated clinic appointments

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The chronic use of any of these medications has the potential to cause complications related to vitamin B12 deficiency, which includes impaired DNA synthesis, impaired cell division, hematopoiesis, hyperhomocysteinemia, and metabolism of odd-chain fatty acids that is necessary in preventing demyelination of nerves

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