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doi: 10.1038/s41443-022-00605-0 62 HamiltonTRCastroLSDelgado JdeCAssisPMSiqueiraAFMendesCMet al
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Calcium has a key role in mitochondrial function and is a primary regulator of oxidative phosphorylation (40)

Plasma methionine and urinary sulfate, pyroglutamate or alpha-hydroxybutyrate are related tests that may be performed for confirmation of significant cysteine deficit

The risk/benefit ratio needs to be carefully evaluated in order to provide the best treatment option to every individual patient

Markers of HBV Infection and CHB Disease Progression The progression of CHB depends on the interaction between the virus and the host's immune response, with the main morbidity burden resulting from long-term liver complications (cirrhosis and HCC) that can develop as a result of a persistent immune response against HBV-infected hepatocytes