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Iran J Basic Med Sci 23(6):730736

Souba WW, Strebel FR, Bull JM, Copeland EM, Teagtmeyer H, Cleary K

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A linear curve is obtained by plotting on a semilog paper the amount of the drug unchanged yet to be eliminated, log ( u u ) versus time, the slope of this curve is /2.3, and the intercept is u

References Health Canada

The PERK pathway intersects with the integrated stress response (ISR) at eIF2 phosphorylation PERK is a type I transmembrane ER protein containing a luminal domain similar to that of IRE1 and a cytosolic S/T protein kinase domain