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Pathol Int (2019) 69(7):4346

TFEB enhances PPAR expression during nutrient stress, whereas PPAR activation (such as fenofibrate) induces TFEB expression and nuclear translocation, amplifying lysosomal gene expression and calcium-mediated clearance of hepatic lipid droplets

Pi, Inorganic phosphate

HER2 amplifications and mutations are considered to be usually unrelated and clinically distinct driver alterations that can be used to segment lung adenocarcinoma patients for targeted therapy [24, 25], and the development of drugs targeting HER2 remains an urgent clinical need [26]

2021;9:E190E194

Moreover, while the pharmacodynamic effects of LDX primarily involve increased dopaminergic and noradrenergic activity, its impact on other neurotransmitter systems and the downstream effects on brain function remain poorly characterised