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We hypothesized that surface modification of poly(lactic-co-glycolic acid) (PLGA) nanoparticles with rabies virus glycoprotein (RVG29) would increase residence time and exposure of encapsulated payload to the CNS compared to non-targeted nanoparticles

doi: 10.1124/jpet.106.114546

Metabolic factors contribute to SARS-CoV-2 tissue tropism and metabolic diseases The COVID-19 pandemic has illuminated how reciprocal regulation of intrinsic tissue metabolic response and whole-body metabolic homeostasis impact the outcome of viral infections

Although preliminary evidence is encouraging, comprehensive studies are needed to definitively establish the therapeutic role of L-carnitine in ME/CFS and to optimize its clinical application

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