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While it is found in meat and dairy and produced by the body, supplementation may offer benefits for weight management, brain function, heart health, and blood sugar control

doi: 10.1016/j.neuro.2020.03.015 38 FratiPKyriakouCDel RioAMarinelliEVergalloGMZaamiSet al

Individuals who follow a plant-based diet or have certain genetic conditions may have lower levels, making it a conditionally essential nutrient

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27 Another study compared a combination oral supplement that included 600 mg/d ALA along with gamma-linolenic acid to a vitamin supplement containing vitamins B1, B6, and B12 over 3 months in 112 patients with moderate to severe CTS.28 Researchers found similar results, with significant pain reduction and improved function in the ALA treatment group with only slightly improved pain reduction in the vitamin B group but with worsened function