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A potential underlying mechanism involves attenuated phosphorylation of p53 at Ser46, which inhibits p53-mediated apoptosis and ferroptosis (Zhang et al., 2022)

However, the use of blinded evaluators (dermatologists who didn't know which photos were "before" and "after") and AI-assisted assessment helps reduce subjective bias in the results

Cre recombinase, a site-specific integrase isolated from the P1 bacteriophage, catalyzes recombination between two of its consensus DNA recognition sites (8)

Packer M, Anker SD, Butler J, Cleland JGF, Kalra PR, Mentz RJ, Ponikowski P

PMID: 42195328 Endocrinology Relaxin Modulates the Genomic Actions and Biological Effects of Estrogen in the Myometrium
