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Hadgraft JW

doi: 10.1016/j.bbrc.2004.10.002

Storage Stability Study a Results are expressed as the mean SD, n = 3

By obtaining synovial fluid from acute GA patients through puncture, the cell population obtained after centrifugation (usually rich in 60-90% neutrophils and monocytes/macrophages) itself represents a natural co-culture system that may closely simulate the inflammatory response in the joint cavity ( Organoid models, as emerging in vitro research platforms, simulate the structure and function of organs in vivo through three-dimensional culture techniques and show unique value in GA research

The full-length adiponectin induces depigmentation via AMPK/ CREB-regulated transcription coactivators (CRTCs)/CREB signaling pathway 104 , but the gAd promotes melanogenesis by activation of the AMPK-p38 MAPK-CREB pathway 105

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