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Zhang T, Wang Y, Xia Q, Tu Z, Sun J, Jing Q, et al

doi: 10.1016/j.it.2008.07.004 Summary Keywords melatonin, fibrosis, therapeutics, protective effects, mechanisms Citation Huang W, Zheng J, Wang M, Du L-Y, Bai L and Tang H (2024) The potential therapeutic role of melatonin in organ fibrosis: a comprehensive review

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These frequent arousals disrupt the continuity and depth of slow-wave sleep, reducing the restorative functions of sleep and further impairing glymphatic clearance of metabolic waste products, including ROS-generating aggregates such as beta-amyloid

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Another large review of 12 studies found that vitamin E helped reduce blood sugar levels, while vitamin C was effective at decreasing levels of oxidative stress