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After 90 days, treated animals showed normalised motor function and improved macroscopic and microscopic structures

Neutral nanoparticles with an intermediate size of about 200 nm penetrate more deeply and remain longer within the buccal epithelium, for example, within the microplicae, than smaller particles of 25 to 50 nm

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Notably, Vgf (nerve growth factor inducible) is specifically upregulated in cells of GCGR-KO mice

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