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The resulting prenylated intermediate, dimethylallyl-toluquinol, would then be cyclized to 5,8-dihydro-2,7-dimethylnaphthalene-1,4-diol, which would subsequently be aromatized to produce chimaphilin (Figure 2)

Never adjust both compounds simultaneously, as this makes it impossible to identify which compound is responsible for any changes in symptoms or blood markers

Joseph Pizzorno, ND