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Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents

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Recent reports have shown that the shear-induced opening of endothelial Piezo1 channels activates the calcium-dependent protease calpain (Li et al., 2014), which in turn cleaves talin (a protein that links membrane integrins to the actin cytoskeleton) to alter integrin-mediated cell adhesion (McHugh et al., 2010)

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Release form Neutral glass vials NS-1, NS-2, USP-1 closed with rubber stoppers for aluminum rolling, 10, 20, 100 and 200 ml each
