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However, setting successive steps of purification, depends on the initial amount of materials, may yield a very low quantity of a protein and low enzyme activity when an active enzyme is subjected to purification

Serotonergic mechanisms regulating the GI tract: experimental evidence and therapeutic relevance

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This result made us consider the possibility that GC deficiency was likely a consequence of an upstream defect leading to compensatory upregulation of steroidogenic enzyme gene expression

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