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But signs and symptoms only tell part of the story

Zhao X, Ueba T, Christie BR, Barkho B, McConnell MJ, Nakashima K, et al
The central nervous system is protected by what is known as the blood-brain barrier (BBB), which prevents toxic molecules from reaching the brain, but also limits the accumulation of drugs in therapeutic doses

K., The Bloodbrain Barrier and Bloodtumour Barrier in Brain Tumours and Metastases, Nature Reviews Cancer 20 (2020): 2641

[DOI] [PubMed] [Google Scholar] 347.Wahyuni W., Diantini A., Ghozali M., Subarnas A., Julaeha E., Amalia R., Sahidin I