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Description
The aberrant activation of Nrf2 in cancer cells leads to increased expression of Glucose-6-phosphate dehydrogenase (G6PD), transketolase (TKT), 6-phosphogluconate dehydrogenase (PGD), and other metabolic enzymes promoting glutamine and glucose metabolism in pentose phosphate pathway (PPP) and increasing synthesis of amino acids participating in metabolic reprogramming required for cell proliferation (Mitsuishi et al
[DOI] [PubMed] [Google Scholar] 186
A NEB Next Ultra Library Preparation Kit (NEB E7530S) was used to prepare 1 g of total RNA for RNA-seq
Dangerous liaisons: pancreatic stellate cells and pancreatic cancer cells
*Correspondence: Ying Wang, [email protected]
The Q-dsAMC probe reacted rapidly with NADH in the co-presence of DT-diaphorase and exhibited fluorescence activation (Fig
