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Nrf2 ( NF-E2-related factor 2 ) is a transcription factor, whereas Keap1 ( kelch-like ECH-associated protein 1 ) is an Nrf2 repressor

They accumulate biofilm in the needle bases that home sterilization (alcohol, boiling, UV wand) can't reliably remove

L.BerkaV.ZweierJ

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Therefore, the future of CAR therapy in autoimmunity depends not only on scientific innovation but also on parallel advancements in affordable manufacturing, thoughtful health policy, and ethical oversight to ensure these transformative treatments can reach the broad patient population in need (109)

doi: 10.3390/ijms22052719