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In this case, the local clock determines when a tissue is more or less sensitive to respond to hormonal stimulation

10.1038/s41598-018-26990-5 169 ShiW.ZhangX.JiangX.YuanH.LeeJ
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Front Chem 7:39 Song H, Quan F, Yu Z et al (2019) Carboplatin prodrug conjugated Fe3O4 nanoparticles for magnetically targeted drug delivery in ovarian cancer cells

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His surgeon, who works with the University of Oregon football team, told him there was no guarantee that surgery would work the first time and he might need follow-up procedures to remove hardware