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Peripheral neuropathy can present as either distal sensory polyneuropathy or vasculitis-mediated mononeuritis multiplex.[22] Diagnosis of Cryoglobulinemic Vasculitis Specific diagnostic criteria or classification for cryoglobulinemic vasculitis have not yet been defined.[22] The diagnosis is typically made from the combination of history, skin findings, low complement levels, presence of cryoglobulins in serum, and histology that shows small vessel inflammation with immune deposits found in the vascular walls.[22] Treatment of HCV-related Cryoglobulinemic Vasculitis The approach to treating HCV-related cryoglobulinemic vasculitis is complex and depends on the severity of the cryoglobulinemia and end-organ involvement

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The cavalier (right) had multiple generalized seizures and showed alternating stupor and hyperexcitability, ataxia, repetitive muscle contractions, and circling to the left side

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