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If the intestines find it difficult to absorb and break down vitamin B12 from food sources, it can cause a deficiency

Ahaliabadeh, Z., Kong, X., Fedorovskaya, E

[DOI] [PubMed] [Google Scholar] 106.Lee JD, Yang WK, Lai CH

Strategies to overcome/penetrate the BBB for systemic nanoparticle delivery to the brain/brain tumor

In toxicology studies, very high doses caused exaggerated pharmacological effects (such as marked weight loss and decreased nutritional intake in animals), but no organ toxicity or unexpected pathology

But it requires large doses that can cause further complications, including peripheral edema and carpal tunnel syndrome