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H 2 O 2 induced oxidative stress in OFs, reflected by a dose-dependent increase in GSSG, a known measure of cell response to ROS ( Figure 1 )

doi: 10.1210/en.2011-1443

The current consensus is that many factors may converge to cause the motor neuron damage typified by ALS (Rothstein 2009)
There has also been some studies on the quantitative measurement of intervertebral discs based on deep learning, but they did not use quantitative data to evaluate IVD degeneration, which may cause subjective bias and limit its clinical application 18,29

This is in agreement with the association of GPX4 with neuromelanin, as Lewy bodies have some association with neurons that have high neuromelanin content [3]

The trio is called Tetrahydrocurcuminoids (THC) and has skin-brightening, anti-inflammatory and antioxidant magic properties
