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Description
These TLS polymerases can accommodate various types of distorted DNA because they have bigger active sites

Balaban, D., Miyawaki, E

Basically, they are present as a proenzyme, but various stimuli can activate the enzymes through cleavage

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[DOI] [PubMed] [Google Scholar] 93.Wada-Hiraike O, Imamov O, Hiraike H, Hultenby K, Schwend T, Omoto Y, Warner M, Gustafsson J-A

The reclassification creates a legal pathway for physician-supervised, pharmacy-compounded peptide access
