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[18] One result of frataxin deficiency is mitochondrial iron overload, which damages many proteins due to effects on cellular metabolism

The CPT system is an important component of the carnitine shuttle which facilitates the transport of long-chain fatty acids from cytosol into the mitochondrial matrix, the site of -oxidation (Figure 2)

Eosinophilic inflammation is related to a type 2 inflammatory profile that leads to the activation of IL-5, the main inflammatory cytokine responsible for the maturation, survival, and activation of eosinophils

demonstrated that cardamom oil (which contains bioactive compounds including -terpinyl acetate, 1,8-cineole (eucalyptol), limonene, and terpinene) exhibits anti-inflammatory effects on carrageenan-induced paw edema in rats by modulating serum levels of tumor necrosis factor , interleukin 6, and interleukin 1 [125]

Int J Sports Med 15, 181185

The number of such meetings plummeted during Makary's tenure