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The SURMOUNT-1 trial reported -22.5% weight reduction at the 15 mg weekly dose across 72 weeks (PMID 35658024)

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This means a lower and less predictable amount of the active compound might reach systemic circulation, potentially requiring higher doses and introducing variability into research findings

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Optional IV Use: Intravenous administration may be considered only when a qualified veterinarian decides it is appropriate

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