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doi: 10.1016/j.redox.2021.102041

Glutathione is a powerful antioxidant composed of three amino acids: glutamine, cysteine, and glycine

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[115] described that phosphoglycerate dehydrogenase (PHGDH), involved in the synthesis of serine and glycine from glucose, is critical for pancreatic tumor cells proliferation and tumorigenesis, mediating cell-tight junctions formation, mTOR activation (through Akt), and protein expression and translation, after interaction with the translation initiation factors eIF4A1 and eIF4E (which seems to be independent of its enzymatic activity)

Moreover, the amounts of lipoic acid available in dietary supplements (50-600 mg) are likely as much as 1,000 times greater than the amounts that could be obtained from the diet

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