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Am Fam Physician 83 [PubMed] 6.Langan RC, Goodbred AJ (2017) Vitamin B12 deficiency: recognition and management

NNMT had previously been identified as upregulated in obese adipose tissue, several solid tumours, and ageing tissue more broadly, where its activity correlates with depleted SAM and elevated 1-methylnicotinamide (MNA)
